The Effect of Aminocaproic Acid and Prednisolone in the Traumatic Hyphema.
- Author:
Jeong Yong KIM
1
;
Gwang Ju CHOI
;
Nam Cheol JI
Author Information
1. Department of Ophthalmology, College of Medicine, Chosun University, Hospital, Kwang-Ju, Korea.
- Publication Type:Original Article
- Keywords:
Aminocaproic acid;
Prednisolone;
Rebleeding;
Traumatic hyphema
- MeSH:
Aminocaproic Acid*;
Diagnosis;
Humans;
Hyphema*;
Medical Records;
Prednisolone*;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
1995;36(4):697-702
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
It is recognized that rebleeding of traumatic hyphema may predispose patients to several complications including decreased visual acuity. We reviewed the medical records of 92 patients(92 eyes) with the diagnosis of nonperforating traumatic hyphema. The relative efficiencies of Aminocaproic acid and systemic Predisolone for reducing rate of rebleeding and their side effects were evaluated under the statistical analysis. Fourty-seven patients received an oral dosage of 50 mg/kg of Aminocaproic acid every 4 hours for 5 days(up to a maximum 30 gm/day), and fourty-five patients took an oral dosage of 0.6 mg/kg of Prednisolone daily in two devided doses. The frequency of rebleeding was not statistically significantly different between the aminocaproic acid treated group(4.3%, 2/47 patients) and the prednisolone treated group(6.7%, 3/45 patients). The developing rates of their acute adverse reaction were statistically different between the aminocaproic acid treated group(44.7%, 21/47 patients) and the prednisolone treated group(20%, 9/45 patients).
