Progress on Copy Number Variation and Its Application in Forensic Medicine.
10.12116/j.issn.1004-5619.2020.02.020
- Author:
Qian Nan XU
1
;
Jia Yi ZHANG
2
;
Cheng Tao LI
1
;
Xi Ling LIU
2
Author Information
1. West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
2. Shanghai Key Laboratory of Forensic Medicine, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai 200063, China.
- Publication Type:Review
- Keywords:
forensic genetics;
copy number variation;
monozygotic twins;
review
- MeSH:
DNA Copy Number Variations;
Forensic Medicine;
Genetic Markers
- From:
Journal of Forensic Medicine
2020;36(2):256-262
- CountryChina
- Language:English
-
Abstract:
Recently, researches on copy number variation （CNV） have extended to every field, such as etiological exploration and precise treatment of complex diseases, as well as genetic breeding and evolution. The unique genetic characteristics of CNV have made people gradually believe that it could be used as a biological genetic marker to solve related problems. With the development of detection technology, application of CNV in forensic medicine will increase gradually. In this paper, the concept and development of CNV, as well as its application in forensic medicine are summarized, to provide new ideas for the practical application of CNV in the future.
