Advancements in Single-cell Sequencing and the Prospect of Its Forensic Application.
10.12116/j.issn.1004-5619.2019.05.017
- Author:
Man CHEN
1
;
Ya Ran YANG
1
;
Hui Juan WU
2
;
Jiang Wei YAN
1
Author Information
1. Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China.
2. Beijing Center for Physical and Chemical Analysis, Beijing 100094, China.
- Publication Type:Review
- Keywords:
forensic genetics;
single-cell sequencing;
genome;
review
- MeSH:
DNA;
Forensic Genetics;
High-Throughput Nucleotide Sequencing;
Humans;
Sequence Analysis, DNA/methods*
- From:
Journal of Forensic Medicine
2019;35(5):602-606
- CountryChina
- Language:English
-
Abstract:
Single-cell sequencing is a technique that analyzes DNA and RNA sequences on the cellular level with next generation sequencing. The ultra high resolution of single-cell sequencing provides new perspectives and opens new frontiers for our understanding of many areas of life sciences, including forensic genome. This paper summarizes the recent advancements in single-cell sequencing and the prospect of its forensic application.
