Pigmentation Phenotype Prediction of Chinese Populations from Different Language Families.
10.12116/j.issn.1004-5619.2019.05.008
- Author:
Qiu Shuang LIANG
1
;
Ming LIU
1
;
Xian Ming TAO
2
;
Fan LIU
2
;
Fa Ming ZENG
3
;
Cai Xia LI
1
;
Wen Ting ZHAO
1
Author Information
1. National Engineering Laboratory for Crime Scene Evidence Investigation and Examination, Key Laboratory of Forensic Genetics, Beijing Engineering Research Center of Crime Scene Evidence Examination, Institute of Forensic Science, Ministry of Public Security, Beijing 100038, China.
2. Beijing Institute of Genomics, Chinese Academy of Sciences, Key Laboratory of Precision Genome Medicine, Beijing 100101, China.
3. School of Forensic Medicine, Kunming Medical University, Kunming 650500, China.
- Publication Type:Journal Article
- Keywords:
forensic genetics;
forensic anthropology;
phenotype;
pigment;
language family
- MeSH:
Adult;
Asian People/genetics*;
China;
Eye Color/genetics*;
Forensic Anthropology;
Forensic Genetics/methods*;
Humans;
Language;
Male;
Phenotype;
Polymorphism, Single Nucleotide;
Reproducibility of Results;
Skin Pigmentation/genetics*
- From:
Journal of Forensic Medicine
2019;35(5):553-559
- CountryChina
- Language:English
-
Abstract:
Objective To predict the pigmentation phenotypes of Chinese populations from different language families, analyze the differences and provide reference data for forensic anthropology and genetics. Methods The HIrisPlex-S multiplex amplification system with 41 loci related to pigmentation phenotypes was constructed in the laboratory, and 2 666 DNA samples of adult males of 17 populations from six language families, including Indo-European, Sino-Tibetan, Altaic, Hmong-Mien, Tai-Kadai and Austro-Asiatic language families distributed in different regions of China were genotyped. The pigmentation phenotype category of each individual was predicted using the online prediction system （https://HIrisPlex.erasmusmc.nl/）, and then the output data were statistically analyzed. Results About 1.92% of the individuals of Asian-European admixed populations from Indo-European and Altaic language families had blue eyes and 34.29% had brown or gold hair. The phenotypes of the color of eyes and hair of other populations had no significant difference, all individuals had brown eyes and black hair. There were differences in skin color of populations of different language families and geographical areas. The Indo-European language family had the lightest skin color, and the Austro-Asiatic language family had the darkest skin color; the southwestern minority populations had a darker skin color than populations in the plain areas. Conclusion The prediction results of pigmentation phenotype of Chinese populations are consistent with the perception of the appearance of each population, proving the reliability of the system. The color of eyes and hair are mainly related to ancestral components, while the skin color shows the differences between language families, and is closely related to geographical distribution of populations.
