DNA Molecular Identification of Human Phenotypic Characteristics--New Progress Over the Past Five Years.
10.12116/j.issn.1004-5619.2019.05.002
- Author:
Hao Tian MENG
1
;
Qiong LAN
2
;
Bo Feng ZHU
1
Author Information
1. Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an 710004, China.
2. School of Forensic Medicine, Southern Medical University, Guangzhou 510515, China.
- Publication Type:Journal Article
- Keywords:
forensic genetics;
forensic anthropology;
phenotyping;
pigmentation;
hair;
age;
body height;
review
- MeSH:
DNA/genetics*;
Databases, Nucleic Acid;
Eye Color/genetics*;
Forensic Anthropology/trends*;
Forensic Genetics/trends*;
Hair Color/genetics*;
Humans;
Phenotype;
Physical Appearance, Body/genetics*;
Skin Pigmentation/genetics*
- From:
Journal of Forensic Medicine
2019;35(5):512-518
- CountryChina
- Language:English
-
Abstract:
Molecular identification of human externally visible characteristic （EVC）, which is also called forensic DNA phenotyping （FDP）, can serve as a "molecular witness" when the routine investigations can not determine the identity of a criminal and the DNA database find no match after comparison. FDP could assist in investigation of cases by inferring the externally visible phenotypic characteristics from DNA obtained from the biological materials left at crime scenes, or unknown corpses. In the last few years, studies on the selection of EVC related molecular markers have been reported frequently and some of the EVCs could already be inferred with a certain accuracy, such as hair color and iris color. Further fundamental research on molecular genetics of human external phenotypic characteristics, as well as the continuous innovation on molecular biological technology would promote the rapid development of DNA molecular identification of human phenotypic characteristics.
