Application of Dispersive Liquid-Liquid Microextraction in Forensic Toxicological Analysis.
10.12116/j.issn.1004-5619.2019.03.016
- Author:
Yu YANG
1
;
Yun Feng ZHANG
2
;
Xin Tong LI
1
;
Fang Lin WANG
2
;
Hong Yuan HE
1
;
Jian HUANG
2
Author Information
1. People's Public Security University of China, Beijing 102600, China.
2. Institute of Forensic Science, Ministry of Public Security, PRC, Beijing 100089, China.
- Publication Type:Review
- Keywords:
forensic toxicology;
dispersion liquid-liquid microextraction;
toxicological analysis;
pretreatment methods;
review
- MeSH:
Forensic Toxicology;
Liquid Phase Microextraction;
Reproducibility of Results;
Solid Phase Extraction;
Solvents
- From:
Journal of Forensic Medicine
2019;35(3):344-348
- CountryChina
- Language:English
-
Abstract:
Currently, the main sample pretreatment methods for forensic toxic analysis are liquid-liquid extraction （LLE） and solid-phase extraction （SPE）. As a simple, convenient, and low-cost LLE method, dispersion liquid-liquid microextraction （DLLME） has high enrichment factor and good extraction efficiency, and therefore has attracted the attention of many researchers in the field of toxicology analysis in recent years. As a multi-functional microextraction method, DLLME has been widely used in the analysis of pesticides, sleeping sedatives, drugs and heavy metal poisons in forensic toxic analysis. Meanwhile, it can also be used in combination with such a variety of analytical instruments as gas chromatography-electron capture detectors （GC-ECD）, high performance liquid chromatography-diode array detectors （HPLC-DAD）. As a sample pretreatment method, DLLME has the advantages of simple operation, less use of organic solvent, reliable results and good reproducibility, thus can meet the requirements of modern court toxic analysis.
