Confirming Indicators of Qualitative Results by Chromatography-mass Spectrometry in Biological Samples.
10.3969/j.issn.1004-5619.2017.02.016
- Author:
Shao Dan LIU
1
;
Da Ming ZHANG
2
;
Wei ZHANG
2
;
Wen Fang ZHANG
2
Author Information
1. School of Forensic Medicine, Shanxi Medical University, Taiyuan 030001, China.
2. Forensic Medical Identification Center of Beijing Municipal Public Security Bureau, Beijing 100192, China.
- Publication Type:Review
- Keywords:
biological sample;
chromatography;
confirming indicator;
forensic toxicology;
mass spectrometry;
qualitative research;
quality control;
review
- MeSH:
Chromatography;
Forensic Toxicology;
Gas Chromatography-Mass Spectrometry;
Mass Spectrometry
- From:
Journal of Forensic Medicine
2017;33(2):181-188
- CountryChina
- Language:Chinese
-
Abstract:
Because of the exist of complex matrix, the confirming indicators of qualitative results for toxic substances in biological samples by chromatography-mass spectrometry are different from that in non-biological samples. Even in biological samples, the confirming indicators are different in various application areas. This paper reviews the similarities and differences of confirming indicators for the analyte in biological samples by chromatography-mass spectrometry in the field of forensic toxicological analysis and other application areas. These confirming indicators include retention time （RT）, relative retention time （RRT）, signal to noise （S/N）, characteristic ions, relative abundance of characteristic ions, parent ion-daughter ion pair and abundance ratio of ion pair, etc.
