Source Identification of Human Biological Materials and Its Prospect in Forensic Science.
10.3969/j.issn.1004-5619.2016.03.011
- Author:
Kai Nan ZOU
1
;
Cheng GUI
2
;
Yu GAO
1
;
Fan YANG
1
;
Huai Gu ZHOU
1
Author Information
1. Key Laboratory of Forensic Evidence and Science Technology, Ministry of Public Security, Institute of Forensic Science, Shanghai Public Security Bureau, Shanghai 200083, China.
2. Institute of Criminal Science and Technology, Changning Branch of Shanghai Public Security Bureau, Shanghai 200336, China.
- Publication Type:Review
- Keywords:
forensic genetics;
genetic markers;
review [publication type];
source
- MeSH:
DNA Methylation;
Forensic Genetics;
Forensic Sciences;
Genetic Markers;
Humans;
MicroRNAs;
RNA, Messenger
- From:
Journal of Forensic Medicine
2016;32(3):204-210
- CountryChina
- Language:English
-
Abstract:
Source identification of human biological materials in crime scene plays an important role in reconstructing the crime process. Searching specific genetic markers to identify the source of different human biological materials is the emphasis and difficulty of the research work of legal medical experts in recent years. This paper reviews the genetic markers which are used for identifying the source of human biological materials and studied widely, such as DNA methylation, mRNA, microRNA, microflora and protein, etc. By comparing the principles and methods of source identification of human biological materials using different kinds of genetic markers, different source of human biological material owns suitable marker types and can be identified by detecting single genetic marker or combined multiple genetic markers. Though there is no uniform standard and method for identifying the source of human biological materials in forensic laboratories at present, the research and development of a series of mature and reliable methods for distinguishing different human biological materials play the role as forensic evidence which will be the future development direction.
