Population Difference Analysis of Allele Frequencies of 24 Y-STR Loci.
10.3969/j.issn.1004-5619.2016.03.007
- Author:
Ru Xin ZHU
1
;
Jun Hong LIU
2
;
Qi ZHAO
1
;
Yuan LIN
1
;
Li LI
1
Author Information
1. Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Institute of Forensic Science, Ministry of Justice, P.R.China, Shanghai 200063, China.
2. Shanghai Hengping Forensic Science Center, Shanghai 200070, China.
- Publication Type:Journal Article
- Keywords:
Y Chromosome;
allele frequencies;
forensic genetics;
polymorphism, genetic;
short tandem repeat sequences
- MeSH:
Alleles;
Asian People/genetics*;
China;
Chromosomes, Human, Y/genetics*;
Gene Frequency;
Genetics, Population;
Haplotypes;
Humans;
Microsatellite Repeats/genetics*;
Polymorphism, Genetic;
Population Groups
- From:
Journal of Forensic Medicine
2016;32(3):189-192
- CountryChina
- Language:English
-
Abstract:
OBJECTIVES:To investigate the population genetic polymorphisms of 24 Y-STR loci in unrelated individuals in Eastern Chinese Han population, and to compare the difference of Han group between Eastern China and Guangdong.
METHODS:The population genetics of 24 Y-STR loci in 268 unrelated Han individuals from Eastern China were analyzed by GFS 24 Y-STR amplification kit. The allele frequencies in Eastern Chinese Han population were compared with the data in Guangdong Han population, and the difference analysis between two groups was performed.
RESULTS:Among the 24 Y-STR loci of 268 unrelated Han individuals from Eastern China, 235 alleles and 267 haplotypes were observed. GD value ranged from 0.564 9 to 0.966 8. The difference between 12 loci (DYS622, DYS552, DYS443, et al.) of Han population in Eastern China and in Guangdong was statistically significance.
CONCLUSIONS:GFS 24Y STR amplification system shows favorable polymorphisms, which can be used in patrilineal genetic relationship identification.