Research of ultra-structural pathological changes of nervous, endocrine and immune system in heroin addicts.
- Author:
Li Hua LI
1
;
Hong YAO
;
Yong He ZHAO
;
Hua ZHU
;
Yu Ming XING
;
Zhong Tang FENG
;
Run Xiang YANG
Author Information
1. Department of Forensic Medicine, Kunming Medical College, Kunming 650031.
- Publication Type:Research Support, Non-U.S. Gov't
- MeSH:
Central Nervous System/ultrastructure*;
Endocrine System/ultrastructure*;
Female;
Genitalia/ultrastructure*;
Heroin Dependence/pathology*;
Humans;
Immune System/ultrastructure*;
Male;
Microscopy, Electron
- From:
Journal of Forensic Medicine
2001;17(3):145-147
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate ultrastructural pathological changes of Heroin-Addicts.
METHODS:Heroin-Addicts' central nervous system, endocrine system, immune system and reproductive system in 4 cases are observed by using transmission electron microscope(TEM).
RESULTS:The changes of central nervous system are mitochondrion swelling, crista fragmentation and disappear. Endoplasmic reticulum dilation, nervous fibres and cell organelles reduction; mitochondrion swelling, Partial crista fragmentation and endoplasmic reticulum dilation are also found in endocrine system; Lymphocytes reduction, cytoplasm ingredient reduction and dead lymphocytes increase in immune system; in reproductive system, spermatogenic cells and cell organelles are reduced in the male and follicle disappeared in the female.
CONCLUSION:Ultra-structural pathological changes of heroin-addicts are presented acute, chronic oxygen deficiency degeneration and necrosis.
