Study on expression of the glycoprotein in myocardial cell membrane of the rat's early myocardial ischemic.
- Author:
Zhao Hui LI
1
;
Hua Lan JING
;
Du Lun WANG
Author Information
1. Department of Forensic Medicine, Sun Yat-sen University of Medical Sciences, Guangzhou 510089. lizhhu@gzsums.edu.cn
- Publication Type:Journal Article
- MeSH:
Animals;
Female;
Immunohistochemistry;
Male;
Membrane Glycoproteins/biosynthesis*;
Myocardial Ischemia/metabolism*;
Myocardium/metabolism*;
Rats;
Rats, Sprague-Dawley
- From:
Journal of Forensic Medicine
2001;17(3):137-141
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore expression of the glycoprotein in early myocardial ischemic.
METHODS:The glycoprotein changes occurred at the early acute cardiac ischemic area induced experimentally by ligation of left coronary artery of 32 SD rats. 6 lectins were measured by means of immunohistochemical methods.
RESULTS:Positive staining of PNA could be observed in ischemic area at 5 min after ischemia, and the positive area increased with the prolongation of ischemic period. It became the strongest for 2 h and then decreased.
CONCLUSION:This experiment proved that myocardial cell membrane in ischemia expressed D-galactose. This may be of some value in forensic medicine practice.
