Cantonese population data of the tetranucleotide repeat locus D7S809 and its application in paternity test.
- Author:
De-Jian LU
1
;
Qiu Ling LIU
;
Xin Rao WU
Author Information
1. Faculty of Forensic Medicine, Sun Yat-sen University of Medical Sciences, Guangzhou, Guangdong 510089.
- Publication Type:Journal Article
- MeSH:
Alleles;
Asian People/genetics*;
Gene Frequency;
Genetics, Population;
Genotype;
Humans;
Microsatellite Repeats/genetics*;
Paternity;
Polymorphism, Genetic
- From:
Journal of Forensic Medicine
2001;17(1):17-62
- CountryChina
- Language:Chinese
-
Abstract:
The tetranucleotide repeat locus D7S809 was investigated in Cantonese population by polymerase chain reaction (PCR) amplification, subsequent polyacryramide gel electrophoresis and silver staining. 14 alleles and 50 genotypes were detected in 190 sample individuals. All alleles differed in size by 4 bp repeat. No interalleles were found. The heterozygosity, power of discrimination and chance of non-paternal exclusion were 0.8613, 0.9645 and 0.7184 respectively. No significant deviations from Hardy-Weinberg equilibrium were found. The D7S809 was a highly polymorphic, stable and accurate type locus and had been successfully applied to 100 paternity test cases.
