The changes of tryptase activity in anaphylactic shock guinea-pigs.
- Author:
Wei GUO
1
;
Yu Chuan CHEN
;
Shui Ping LIU
;
Jian Ding CHENG
Author Information
1. Department of Forensic Pathology, Sun Yat-sen University of Medical Sciences, Guangzhou, 510080.
- Publication Type:Journal Article
- MeSH:
Anaphylaxis/enzymology*;
Animals;
Female;
Forensic Medicine;
Guinea Pigs;
Male;
Serine Endopeptidases/metabolism*;
Tryptases
- From:
Journal of Forensic Medicine
2001;17(4):212-213
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the changes of the activity of tryptase of sera, lungs and bronchial tubes in the guinea-pigs which suffered from hetero-serum anaphylactic shock.
METHODS:Sera and tissues were collected from anaphylactic shock guinea-pigs, and the enzyme activity was tested colormetrically using special substrate, BAPNA.
RESULTS:The activity of tryptase of sera, lungs and bronchial tubes increased significantly in Anaphylactic guinea-pigs compared with control group.
CONCLUSION:The changes of tryptase activity are helpful to diagnose anaphylactic shock.
