Fos expression in rat skin after different incised wound healing interval.
- Author:
Ning Guo LIU
1
;
Zi Qin ZHAO
;
Yun Ju GU
;
Yi Jiu CHEN
;
Zu Kang YAN
;
Yan Ping LIAO
Author Information
1. Institution of Forensic Sciences of Ministry of Justice, Shanghai 200063. liuningguo@163.net
- Publication Type:Journal Article
- MeSH:
Animals;
Genes, Immediate-Early;
Immunohistochemistry;
Male;
Proto-Oncogene Proteins c-fos/biosynthesis*;
Rats;
Rats, Sprague-Dawley;
Skin/metabolism*;
Time Factors;
Wounds and Injuries/metabolism*
- From:
Journal of Forensic Medicine
2001;17(4):196-197
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the expression of c-fos in rats' skin during wound healing.
METHODS:Immunohistochemistry was conducted on paraffin section from incised wounding model of rat skin.
RESULTS:Fos protein improved from the time of 10 min after wounding in the wound edge, then it reached peak at 3 h. 24 h after injury, the quantity of Fos expression had no difference with that of normal skin.
CONCLUSION:Fos is sensitive after wound, but should be used with other criteria in wounding interval estimation as it's unstediness.
