Recent progress of study on single nucleotide polymorphisms.
- Author:
Dai Xin HUANG
1
;
Lin ZHANG
;
Mei Yun WU
Author Information
1. College of Forensic Medicine, West China University of Medical Sciences, Chengdu 610041.
- Publication Type:Review
- MeSH:
Chromosome Mapping;
Genetic Markers;
Genetics, Population;
Humans;
Polymorphism, Single Nucleotide
- From:
Journal of Forensic Medicine
2001;17(2):122-125
- CountryChina
- Language:Chinese
-
Abstract:
Single nucleotide polymorphisms (SNPs) is a new genetic marker system following RFLP and microsatellite polymorphism. It has been shown to have the characteristics of high-density, inheritance stability and facilitation in analysis automation. SNPs can be detected by electrophoresis, endonuclease-cleavage, PCR and sequencing, and can be used extensively in gene mapping, disease-correlativity analysis, population genetics and drug research.
