A study on the relationship between postmortem interval and the changes of DNA content in the kidney cellule of rat.
- Author:
Liang LIU
1
;
Dong Bing PENG
;
Yan LIU
;
Wei nian DENG
;
Ya Ling LIU
;
Jin Jun LI
Author Information
1. Department of Forensic Medicine, Tongji Medical University, Wuhan 430030. LiuLiang@mails,tjmu.edu.cn
- Publication Type:Journal Article
- MeSH:
Animals;
Cell Nucleus/metabolism*;
DNA/metabolism*;
Image Processing, Computer-Assisted;
Kidney/cytology*;
Male;
Postmortem Changes;
Rats;
Time Factors
- From:
Journal of Forensic Medicine
2001;17(2):65-68
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study changes of DNA content in the kidney cellule of rats and relationship with the postmortem interval.
METHODS:This experiment chose seven parameter of cell nuclear, including the area and integral optical density, determined the changes of DNA content in the kidney cellule of 15 rats at different intervals between 0 and 48 h postmortem with auto-TV-image system.
RESULTS:The degradation rate of DNA in nuclear has a certainty relationship to early PMI(in 48 h) of rat, and get binomial regress equation.
CONCLUSION:Determining the quantity of DNA in nuclear should be an objective and exact way to estimate the PMI.
