Disseminated Superficial ACtinic Porokeratosis Occuring in 3 Generations.
- Author:
Eun Jung CHUNG
;
Tae Yoon KIM
;
Hyung Ok KIM
;
Chung Won KIM
;
Won HOUH
- Publication Type:Case Report
- MeSH:
Abdomen;
Extremities;
Family Characteristics*;
Humans;
Porokeratosis*;
Solar System;
Ultraviolet Rays;
Wills
- From:Korean Journal of Dermatology
1981;19(6):963-967
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Disseminated superficial actinic porokeratosis (DSAP) has an autosomal dominant mode of inheritance with reduced penetration at young age, characterized by multiple superficial keratotic lesions surrounded by a slightly raised border. The aggrevation of the lesion by exposing UV light indicates that phenotypic expression of gene regluating DSAP is related to sun light. We observed a family of which 13 members had DSAP in 3 successive generations. They were grandrnother, two sons of her 3 offsprings, 2 grandsons and 8 granddaughters. Lesions of all cases were found on the sun exposed areas, especially, face, extremities and upper trunk but exceptionally one had a lesion on the unex posed area, abdomen below the iliac crest. The number of lesions of the individual patient were 12-116, and there appeared to be increasing number of lesions with age.
