Eletronmicroscopic Study of Generalized Syringoma.
- Author:
Yoon Kee PARK
;
Jin Soo KANG
;
Sung Nack LEE
;
Chung Sook KIM
- Publication Type:Case Report
- MeSH:
Abdomen;
Adenoma;
Adolescent;
Adult;
Axilla;
Cytoplasm;
Dermis;
Eyelids;
Female;
Glycogen;
Humans;
Larva;
Microvilli;
Neck;
Phenobarbital;
Puberty;
Skin;
Sweat;
Syringoma*;
Thorax;
Vulva
- From:Korean Journal of Dermatology
1981;19(6):975-982
- CountryRepublic of Korea
- Language:English
-
Abstract:
Syringoma is a benign adenoma which usually appear during puberty or adolescence. The lesions are limited to the lower eyelid but may occur on the chest, axillae, abdomen, neck, anterior chest and vulva or be generalized. We recently had an opportunity to observe a 42 year-old woman with generalized syringoma. In histopathologic study of the skin lesion, the numerous cystic and tubular ducts were showed on upper dermis and mid-dermis. Large dilated cysts were usually located in the upper derrnis. A comma-like excrescence similar to tadpoles and solid epithelial cord or ductal structure were showed. In electromicroscopic study, the luminal border of the inner cells was lined with numerous short microvilli and the cytoplasrn showed a periluminal filamment, keratohyaline granules, multivesiculated dense bodies. The outer cells had elongated nucleic and glycogen rich cytoplasm. The cells were connected by well developed desmoaome. The lumina. contained numerous small vesicles and a few multivesiculated bodies. According to these results, this case showed the similar findings of imrnature intraepidermal eccrine sweat duct in electronmicroscopic study.
