Progress on pharmacological activities and hepatotoxicity of bavachinin
10.12206/j.issn.2097-2024.202204031
- VernacularTitle:补骨脂二氢黄酮甲醚的药理活性及肝毒性研究进展
- Author:
Rongrui ZHOU
1
;
Yanping WEI
2
;
Wei CHEN
1
;
Qianqian DING
3
;
Jinxin WANG
1
;
Xianpeng ZU
1
Author Information
1. Basic Medicine School, b. School of Pharmacy, Naval Medical University, Shanghai 200433, China.
2. School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
3. School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China.
- Keywords:
bavachinin;
pharmacological activity;
anti-tumor;
anti-virus;
anti-diabetes;
neuroprotective;
anti-inflammatory;
liver toxicity
- From:
Journal of Pharmaceutical Practice
2023;41(8):465-471
- CountryChina
- Language:Chinese
-
Abstract:
Bavachinin is a dihydroflavone isolated from dried ripe fruits of Psoralea corylifolia L.，which has various pharmacological activities, such as anti-tumor, anti-virus, anti-diabetes, anti-inflammatory and neuroprotective, and good potential in clinical applications. With the increasing concern about the safety of P. corylifolia applications in clinical, the bavachinin has been found to be one of the main components causing liver injury. In this paper, the pharmacological activities and hepatotoxicity of bavachinin in the recent 20 years were reviewed, in order to provide reference for the further study and clinical application.
