Medical research progresses on sodium dichloroacetate
10.12206/j.issn.2097-2024.202105132
- VernacularTitle:二氯乙酸钠的医学研究进展
- Author:
Cheng LU
1
;
Yu JIANG
2
;
Cheng PENG
1
;
Lijun YANG
1
;
Hehui XIE
1
Author Information
1. School of Public Health and Hongqiao International Institute of Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
2. Department of Pharmacy, Changzheng Hospital，Naval Medical University, Shanghai 200003, China.
- Keywords:
sodium dichloroacetate;
pharmacology;
derivatives;
toxicological studies
- From:
Journal of Pharmaceutical Practice
2023;41(8):455-458
- CountryChina
- Language:Chinese
-
Abstract:
Sodium dichloroacetate (DCA) is a small molecule drug usually administered orally. It has therapeutic effects against several diseases, such as metabolic syndrome, cardiovascular and cerebrovascular diseases, and several solid tumors. In this review, the research progresses of DCA in mechanism of action, pharmacological action and toxicological studies were summarized from the recent literatures on the pharmacological actions of DCA.
