Evaluation of Visual Acuity of Ametropia with Visual Event-Related Potential Nogo-P3 Component.
10.12116/j.issn.1004-5619.2020.200406
- Author:
Fu-Quan JIA
1
;
Xin-Yuan ZHANG
1
;
Fang-Liang LUO
1
;
Yan-He XIONG
1
;
Long-Long CHENG
1
;
Ji-Hui LIU
1
Author Information
1. School of Forensic Medicine, China Medical University, Shenyang 110122, China.
- Publication Type:Journal Article
- Keywords:
Nogo-P3;
ametropia;
amplitude;
event-related potential;
forensic medicine;
latency;
vision;
visual acuity
- MeSH:
Electroencephalography;
Evoked Potentials/physiology*;
Humans;
Photic Stimulation;
Reaction Time/physiology*;
Refractive Errors;
Visual Acuity
- From:
Journal of Forensic Medicine
2022;38(3):355-359
- CountryChina
- Language:English
-
Abstract:
OBJECTIVES:To analyze the Nogo-P3 component of event-related potential (ERP) in the process of visual acuity processing, to provide electrophysiological evidence for objective evaluation of visual acuity.
METHODS:Twenty-six subjects with no other ocular diseases except for ametropia were recruited, and all subjects had uncorrected visual acuity both eyes 1/10 (evaluated using Monoyer chart). Block letter E with different visual angles and directions were used as graphic stimuli. The Go/Nogo paradigm was used for ERP studies. The visual angle of Go stimulation angle was 1°15', Nogo stimuli were 1°15', 55', 24' and 15'. The visual acuity test was performed on each of the two naked eyes separately in all subjects, and the characteristics of the Nogo-P3 component were analyzed.
RESULTS:The latency of Nogo-P3 showed no difference between the stimuli of 1°15' and 55', and between Nogo stimulation angle 24' and 15'. There was significant difference between Nogo stimulation angle 1°15' and 24', and between Nogo stimulation angle 1°15' and 15' (P<0.05). There was significant difference between Nogo stimulation angle 55' and 24', and between Nogo stimulation angle 55' and 15' (P<0.05). No significant differences were observed in the Nogo-P3 amplitude among Nogo stimulation.
CONCLUSIONS:In the Go/Nogo paradigm, Nogo-P3 can reflect the cognitive response of subjects to Nogo stimulation, which can be used for objective evaluation of visual acuity.
