Research Progress of Exosomal microRNA in Cardiovascular Disease and Its Forensic Application Prospects.
10.12116/j.issn.1004-5619.2020.400911
- Author:
Xiao-Nan MA
1
;
Lu LU
2
;
Yan-Tong HUANG
1
;
Chang-Qian CEN
1
;
Feng-Yuan SU
3
;
Yi SHI
1
;
Zhi-Peng CAO
1
Author Information
1. Liaoning Province Key Laboratory of Forensic Bio-evidence Science, School of Forensic Medicine, China Medical University, Shenyang 110122, China.
2. Haimen Branch of Nantong Public Security Bureau, Nantong 226100, Jiangsu Province, China.
3. The Third Clinical Department, China Medical University, Shenyang 110122, China.
- Publication Type:Journal Article
- Keywords:
cardiovascular disease;
exosome;
forensic pathology;
microRNA (miRNA);
review;
sudden cardiac death
- MeSH:
Cardiovascular Diseases/genetics*;
Exosomes/genetics*;
Humans;
MicroRNAs/genetics*
- From:
Journal of Forensic Medicine
2022;38(2):258-262
- CountryChina
- Language:English
-
Abstract:
Exosomal microRNAs (miRNAs) are miRNAs that are mediated by exosomes to achieve cell-to-cell communication, and they are widespread in organisms. In recent years, the key role of the multiple biological functions of exosomal miRNAs in the occurrence and development of cardiovascular diseases has been confirmed by a large number of studies, which has become a hot spot in clinical and basic research. Sudden cardiac death caused by cardiovascular disease is one of the important contents in forensic medical identification. This article introduces the research progress of cardiovascular disease prediction, treatment and prognosis on exosomal miRNA. The prospects of the application in forensic medical identification are discussed.
