Application Prospect of MicroRNA in Skin Wound Age Estimation.
10.12116/j.issn.1004-5619.2020.400709
- Author:
Jian CHENG
1
;
Long-Long SUO
1
;
Lin-Lin WANG
1
;
Rui ZHAO
1
;
Da-Wei GUAN
1
Author Information
1. Department of Forensic Pathology, School of Forensic Medicine, China Medical University, Shenyang 110122, China.
- Publication Type:Journal Article
- Keywords:
forensic pathology;
microRNA;
review;
skin;
wound age estimation
- MeSH:
Biomarkers;
Humans;
MicroRNAs/genetics*;
Skin/injuries*;
Soft Tissue Injuries;
Wound Healing
- From:
Journal of Forensic Medicine
2021;37(6):841-846
- CountryChina
- Language:English
-
Abstract:
Wound age estimation is one of the major tasks in forensic practice. However, relatively accurate estimation of the wound age is still a conundrum and research spotlight world-widely. Studies show that microRNAs (miRNAs) are involved in the whole process of the skin wound repair, and miRNAs, as biomarkers, might be used to estimate the time of skin injury owing to their characteristic advantage. This paper summarizes the miRNA fundamental function, properties, current research progress in the estimation of wound age, and its limitations, and put forward prospect of potential application and research based on miRNAs in estimation of wound age.
