A Case of Infliximab-induced Multifocal Motor Neuropathy in a Patient with Rheumatoid Arthritis and Literature Review.
10.4078/jrd.2016.23.4.250
- Author:
Bomi SEO
1
;
Yeong Jin JEONG
;
Seokchan HONG
;
Yong Gil KIM
;
Chang Keun LEE
;
Bin YOO
Author Information
1. Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Infliximab;
Motor neuropathy;
Rheumatoid arthritis
- MeSH:
Arthritis, Psoriatic;
Arthritis, Rheumatoid*;
Colitis, Ulcerative;
Crohn Disease;
Female;
Humans;
Inflammatory Bowel Diseases;
Infliximab;
Korea;
Middle Aged;
Peripheral Nervous System Diseases;
Spondylarthropathies;
Spondylitis, Ankylosing;
Tumor Necrosis Factor-alpha
- From:Journal of Rheumatic Diseases
2016;23(4):250-255
- CountryRepublic of Korea
- Language:English
-
Abstract:
Tumor necrosis factor (TNF) inhibitors are increasingly used in treatment of rheumatoid arthritis (RA), ankylosing spondylitis, psoriatic arthritis, and inflammatory bowel diseases including Crohn's disease and ulcerative colitis. Rarely, anti-TNF therapy is associated with neurological complications, including both central and peripheral nervous system disorders. To the best of our knowledge, only one case of infliximab-associated multifocal motor neuropathy with conduction block in a patient with spondyloarthropathy has been reported to date in Korea. Here, we report on the case of a 58-year-old Korean woman affected by RA who developed multifocal motor neuropathy after infliximab treatment.
