Research Progress on Molecular Markers Related to Unexplained Sudden Cardiac Death and Its Forensic Application.
10.12116/j.issn.1004-5619.2020.400507
- Author:
Xiang-Wang HE
1
;
Lin-Feng LI
1
;
Fu ZHANG
2
;
Li-Bing YUN
1
Author Information
1. West China School of Basic Medical Sciences & Forensic Medicine, Chengdu 610041, China.
2. Key Laboratory of Forensic Pathology, Guangdong Public Security Department, Guangzhou 510050, China.
- Publication Type:Review
- Keywords:
forensic pathology;
molecular biomarker;
review;
sudden cardiac death
- MeSH:
Biomarkers;
Death, Sudden, Cardiac/pathology*;
Forensic Medicine;
Forensic Pathology;
Heart;
Humans
- From:
Journal of Forensic Medicine
2021;37(5):687-693
- CountryChina
- Language:English
-
Abstract:
Routine pathological examination of unexplained sudden cardiac death (USCD) lacks significant morphological characteristics. In the field of forensic medicine, molecular biology methods have been used to find the cause of death by detecting genes and research related to the mechanism of sudden cardiac death has been carried out. From the molecular pathology point of view, the application of multiple levels of biomarkers to resolve the causes of USCD has already shown potential and provides an important path for forensic identification of USCD. This article reviews the latest research progress on USCD-related genes, RNA, proteins and USCD, and summarizes forensic application.
