Forensic Investigation of Goldeneye™ DNA ID 22NC Kit.
- Author:
Yuan LIN
;
Ting-zhi QUE
;
Zhen-min ZHAO
;
Su-hua ZHANG
- Publication Type:Journal Article
- MeSH:
Alleles;
Asian People/genetics*;
China;
Ethnicity/genetics*;
Forensic Genetics/methods*;
Gene Frequency;
Genetic Loci/genetics*;
Genetic Markers/genetics*;
Genetics, Population;
Genotype;
Humans;
Polymorphism, Genetic;
Reagent Kits, Diagnostic
- From:
Journal of Forensic Medicine
2015;31(4):280-283
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the genetic data of 21 autosomal STR included in Goldeneye™ DNA ID 22NC Kit in Chinese Han nationality and to evaluate the forensic application.
METHODS:By detected 500 unrelated healthy individuals in Chinese Han nationality of East China with Goldeneye™ DNA ID 22NC Kit, allele frequencies, population genetics parameters and linkage disequilibrium information of the 21 autosomal STR were statistically analyzed.
RESULTS:In the 21 autosomal STR, no deviations from Hardy-Weinberg equilibrium were detected and all loci were independent form each other. DP values of 21 autosomal STR were all above 0.85, and the combined discrimination power was 1-3.616 5 x 10(-26). Combined mean exclusion chance of this system in duo cases was 1-2.786 81 x10(-6), in trio cases was 1-8.545 82 x 10(-1).
CONCLUSION:Twenty-one autosomal STR included in Goldeneye™ DNA ID 22NC Kit are highly polymorphic in the Han nationality. Combined with Goldeneye™ DNA ID 20A Kit, the kit can satisfy the needs for full-sibling testing and facilitate the solution of this kind of case tools.
