The cell growth and tumor suppressive genes
- Author:
Phi Thi Phi Phan
- Publication Type:Journal Article
- Keywords:
cancer
- MeSH:
neoplasms;
Cell Growth Processes
- From:Journal of Medical Research
1998;7(3):36-42
- CountryViet Nam
- Language:Vietnamese
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Abstract:
Cell’s development is divided two phase: growth and differentiation to mature cell with different biological functions and then death. There is a balance between growth and death to maintain the endothelial balance. The disorder of this balance can cause the malignant diseases. The immortality is the most important property of malignant cells, not for normal cells. The tumor suppressive genes include gene P53; gene P21 cip1 gene P 300/CBP, gene BTG 2 and gene P73. Genes play role of repaire of damaged DNA include RM, RPA, BRCA1 and BRCA2. The lost telomerase or inhibition of telomerase will exclude the tumor cells.
