Genetic polymorphism of nine non-CODIS STR loci in Hunan Province-based Chinese Han population.
- Author:
Juan-juan GUO
;
Ying LIU
;
Ya-dong GUO
;
Jie YAN
;
Yun-feng CHANG
;
Ji-feng CAI
;
Ting LU
;
Zha LAGABAIYILA
- Publication Type:Research Support, Non-U.S. Gov't
- MeSH:
Alleles;
Asian People/genetics*;
China;
Ethnicity/genetics*;
Gene Frequency;
Genetics, Population;
Genotype;
Humans;
Male;
Microsatellite Repeats/genetics*;
Polymorphism, Genetic
- From:
Journal of Forensic Medicine
2014;30(6):441-445
- CountryChina
- Language:English
-
Abstract:
OBJECTIVE:To determine the allelic frequency distribution and genetic parameters of nine non-CODIS DNA index systems of the short tandem repeat (STR) loci (D2S1772, D6S1043, D7S3048, D8S1132, D11S2368, D12S391, D13S325, D18S1364, and GATA198B05).
METHODS:A total of 353 blood samples were collected, extracted, amplified, and analyzed from unrelated healthy individuals of Han nationality in Hunan Province, China.
RESULTS:One hundred and fourteen alleles were observed in the population with corresponding allelic frequencies ranged from 0.001 0 to 0.323 0. For all the nine non-CODIS STR loci, the observed genotypic data showed no significant deviations from the Hardy-Weinberg equilibrium. The Ho, He, PIC, DP, and PE of the studied non-CODIS STR loci ranged from 0.1080 to 0.1950, 0.8050 to 0.8920, 0.7700 to 0.8600, 0.9250 to 0.9660 and 0.6070 to 0.7800, respectively.
CONCLUSION:Nine non-CODIS STR loci have high degrees of polymorphisms, which may be useful in individual forensic identification and parentage testing in forensic practice.
