Forensic application of 30 InDel loci in Han and She nationalities of Eastern China.
- Author:
Zhen HU
;
Zheng WANG
;
Su-hua ZHANG
;
Shu-min ZHAO
;
Ru-xin ZHU
;
Kuan SUN
;
Cheng-tao LI
- Publication Type:Journal Article
- MeSH:
Asian People/genetics*;
China;
Ethnicity/genetics*;
Female;
Forensic Genetics;
Gene Frequency;
Genetic Variation;
Genetics, Population;
Humans;
INDEL Mutation/genetics*;
Polymorphism, Genetic
- From:
Journal of Forensic Medicine
2014;30(5):337-345
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the forensic application value of 30 insertion/deletion (InDel) loci included in Investigator DIPplex Kit in Han and She nationalities of Eastern China.
METHODS:A total of 565 unrelated individuals in Han nationality and 119 ones in She nationality of Eastern China were investigated using Investigator DIPplex Kit. Allele frequencies, population genetics parameters of the 30 InDel loci were statistically calculated.
RESULTS:In Han nationality, the mean Ho was 0.413 3, the mean DP was 0.551 1, the mean PIC was 0.320 0. And in She nationality, the mean Ho was 0.389 6, the mean DP was 0.543 3, the mean PIC was 0.310 0. No deviation from Hardy-Weinberg equilibrium was observed in Han and She nationalities (P > 0.05).
CONCLUSION:The 30 loci in Investigator DIPplex Kit show good genetic diversity in Han and She nationalities, and could be used as a supplemental tool for some special paternity cases.
