Relationship between genetic polymorphism of dopamine receptor and schizophrenia and its forensic significance.
- Author:
Jun YAO
;
Bao-Jie WANG
- Publication Type:Review
- MeSH:
Forensic Medicine;
Humans;
Mental Disorders;
Polymorphism, Genetic;
Psychotic Disorders;
Receptors, Dopamine/genetics*;
Schizophrenia/genetics*;
Schizophrenic Psychology
- From:
Journal of Forensic Medicine
2014;30(3):202-206
- CountryChina
- Language:Chinese
-
Abstract:
Schizophrenia is a common but complex mental disorder affected by multiple factors. Forensic psychiatric assessment of schizophrenia involves evaluations on many aspects, but there is no effective biological identification index for schizophrenia. Researches indicate that dysfunction of dopaminergic neurotransmission plays an important role in the pathogenesis of schizophrenia. Our study reviews the classification, genetic structure of dopamine receptors and the recent pertinent studies between the dopamine receptors and schizophrenia and its forensic significance.
