Changes of oscillatory potentials of electroretinogram after methanol intoxication in rats.
- Author:
Dong-Mei LIU
;
Shu ZHOU
;
Jie-Min CHEN
;
Shu-Ya PENG
;
Wen-Tao XIA
- Publication Type:Journal Article
- MeSH:
Animals;
Electroretinography;
Methanol/poisoning*;
Rats;
Retina/physiopathology*
- From:
Journal of Forensic Medicine
2014;30(3):178-180
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the characters of oscillatory potentials (OPs) of electroretinogram (ERG) after methanol intoxication in rats.
METHOD:The SD rat models of methanol intoxication were established and divided into control group, 3-day intoxication group, 7-day intoxication group. The changes of OPs of ERG were recorded in a dark room.
RESULTS:The total amplitudes of 3-day and 7-day intoxication groups decreased approximately 50% compared with that of the control group, while the schedule delayed approximately 16% and 61%, respectively.
CONCLUSION:The characters of methanol intoxication in rats included delay in schedule and decline in the total amplitude of OPs.
