ApoB gene genetic polymorphism of Han nationality and Mongolian nationality in midwest area of Inner Mongolia.
- Author:
Yang LIU
;
Jun JI
;
Wu-Ren-Tu-Ya BAO
;
Fan YANG
;
Hai-Rong WU
- Publication Type:Journal Article
- MeSH:
Alleles;
Apolipoprotein B-100/genetics*;
Asian People/genetics*;
China;
Ethnicity;
Gene Frequency;
Genotype;
Humans;
Mongolia;
Polymerase Chain Reaction;
Polymorphism, Genetic;
Polymorphism, Restriction Fragment Length
- From:
Journal of Forensic Medicine
2014;30(1):52-54
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study ApoB gene genetic polymorphism of Han nationality and Mongolian nationality in midwest area of Inner Mongolia.
METHODS:Some unrelated individuals of Han nationality and Mongolian nationality in midwest area of Inner Mongolia were selected. Polymerase chain reaction-restriction fragment length polymorphism technology was used to check the presence of Xba I (X+) and EcoR I (E-) sites of rare alleles. The genotype frequency, allelic frequency and population genetics parameters were calculated.
RESULTS:The frequencies of Xba I (X+) and EcoR I (E-) rare alleles were 2% and 4.6% in Han population. There was no Xba I (X+) or EcoR I (E-) rare alleles found in Mongolian nationality.
CONCLUSION:The allelic frequencies of ApoB gene Xba I and EcoR I sites are very different in different races. These sites may be used in identification of ethnicity.
