1483 cases of paternity test with STR loci mutation.
- Author:
Li SHUAI
;
Jun WANG
;
Qiang JING
;
Bin XU
;
Qin SU
;
Yun-Juan LI
;
Hui LI
- Publication Type:Journal Article
- MeSH:
China;
DNA;
DNA Fingerprinting;
Female;
Gene Frequency;
Genetic Markers;
Humans;
Microsatellite Repeats;
Mutation;
Paternity;
Polymorphism, Genetic
- From:
Journal of Forensic Medicine
2014;30(1):44-46
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe and analyze the mutation phenomenon of 17 STR loci of PowerPlex 18D Kit in paternity test of Yunnan population.
METHODS:The DNA was extracted by Chelex-100 method. The PowerPlex 18D Kit was used to test 1,483 cases and their conclusions of paternity tests were verified.
RESULTS:In the 1,483 cases, 1,047 were parental triplet and 436 were uniparental diad. A total of 2,530 times of meiosis was observed. One STR locus mutation was observed in 24 cases. And 11 mutation loci were found in the 17 STR loci.
CONCLUSION:STR loci mutation is a common phenomenon. We should collect the data of STR loci mutation, choose other good polymorphism, low mutation rate of genetic markers, to ensure that the results are accurate and reliable.
