Determination of 33 inorganic elements in human hair by electricity plate digestion and inductively coupled plasma-mass spectrometry.
- Author:
Ru-Xin LUO
;
Dong MA
;
Su-Jing ZHANG
;
Xian-Yi ZHUO
- Publication Type:Journal Article
- MeSH:
Electricity;
Hair/chemistry*;
Humans;
Limit of Detection;
Mass Spectrometry/methods*;
Microwaves;
Reference Standards;
Sensitivity and Specificity;
Trace Elements/analysis*
- From:
Journal of Forensic Medicine
2013;29(6):425-430
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish the electricity plate digestion and inductively coupled plasma-mass spectrometry (ICP-MS) method for determination of 33 inorganic elements in human hair.
METHODS:Lithium (6Li), Germanium (72Ge), Yttrium (89Y), Indium (115In), and Terbium (159Tb) were used as internal standards. The electric heating board digestion in a mixture of nitric acid and hydrogen peroxide was used as the pre-treatment of the hair. Thirty-three inorganic elements in human hair were analyzed by ICP-MS method.
RESULTS:The detection limit of ICP-MS was 0.0001 microg/g(Th)-10.9 microg/g (Ca) and the limit of quantitation was 0.0005 microg/g (Th)-25 microg/g (Ca). The recovery rate of this method was 86%-113%. The RSD for the intra-day and inter-day were less than 9.2%. The method was not statistically different from microwave digestion method.
CONCLUSION:This method is highly efficient and accurate. It can be used for analysis of 33 inorganic elements in human hair.
