Development of Chinese forensic Y-STR DNA database.
- Author:
Jian-Ye GE
1
;
Jiang-Wei YAN
;
Qun XIE
;
Hong-Yu SUN
;
Huai-Gu ZHOU
;
Bin LI
Author Information
1. Health Science Center, University of North Texas, Texas 76107, USA. Jianye.Ge@unthsc.edu
- Publication Type:Review
- MeSH:
Asian People/genetics*;
Chromosomes, Human, Y;
DNA/genetics*;
DNA Fingerprinting;
Databases, Nucleic Acid;
Female;
Forensic Medicine/methods*;
Genetics, Population;
Genotype;
Humans;
Male;
Microsatellite Repeats;
Mutation;
Polymerase Chain Reaction;
Reagent Kits, Diagnostic;
Software
- From:
Journal of Forensic Medicine
2013;29(3):212-221
- CountryChina
- Language:Chinese
-
Abstract:
Y chromosome is a male-specific paternal inherited chromosome. The STR markers on Y chromosome have been widely used in forensic practices. This article summarizes the characteristics of Y-STR and some factors are considered of selecting appropriate Y-STR markers for Chinese population. The prospects of existing and potential forensic applications of Y-STR profiles are discussed including familial excluding, familial searching, crowd source deducing, mixture sample testing, and kinship identifying. The research, development, verification of Y-STR kit, Y-STR mutation rate, and search software are explored and some suggestions are given.
