Developments in determination of elements using ICP-MS in blood and urine.
- Author:
Su-Jing ZHANG
1
;
Xian-Yi ZHUO
;
Dong MA
Author Information
1. School of Pharmacy, Medical College of Soochow University, Suzhou 215123, China.
- Publication Type:Review
- MeSH:
Body Fluids/chemistry*;
Humans;
Mass Spectrometry/methods*;
Metals, Heavy/urine*;
Microwaves;
Sensitivity and Specificity;
Specimen Handling/methods*;
Trace Elements/urine*
- From:
Journal of Forensic Medicine
2012;28(6):456-463
- CountryChina
- Language:Chinese
-
Abstract:
Inductively coupled plasma-mass spectrometry (ICP-MS) is the most common technique for elements analysis at present. ICP-MS with high sensitivity and wide linear range can be applied to multi-elements analysis in blood and urine. This paper reviews the common means of sample pretreatment (direct dilution method and wet digestion method), the method for correction of mass spectral interference and non-interference, the main influence factors of analysis results, and provides an outlook of the application of ICP-MS in forensic toxicological analysis.
