Application of diffusion tensor imaging and 1H-magnetic resonance spectroscopy in diagnosis of traumatic brain injury.
- Author:
Zhao ZHAO
1
;
Jian-yun YU
;
Kun-hua WU
;
Hua-lin YU
;
Ao-xiang LIU
;
Yu-hua LI
Author Information
1. Department of Forensic Medicine, Kunming Medical University, Kunming 650500, China. 327164152@qq.com
- Publication Type:Review
- MeSH:
Animals;
Axons/pathology*;
Brain/pathology*;
Brain Concussion/pathology*;
Brain Injuries/pathology*;
Diagnosis, Differential;
Diffuse Axonal Injury/pathology*;
Diffusion Tensor Imaging;
Humans;
Magnetic Resonance Spectroscopy/methods*;
Nerve Fibers, Myelinated/pathology*;
Severity of Illness Index
- From:
Journal of Forensic Medicine
2012;28(3):207-210
- CountryChina
- Language:Chinese
-
Abstract:
Mild traumatic brain injury (mTBI) is a common type of brain disorders among young adults. The dysfunction of the brain is often exacerbated due to diffuse axonal injury (DAI) which based on the injury of white matter fibers and axons. Since mild and moderate brain injury or DAI are diffuse and subtle, conventional CT and MRI are difficult to make a positive diagnosis. Recent clinical study indicated that functional magnetic resonance imaging has a high detection rate in the diagnosis of acute mild and moderate brain injury, especially the diffusion tensor imaging (DTI) and 1H-magnetic resonance spectroscopy (1H-MRS). This paper has reviewed the principles and characteristics of DTI and 1H-MRS, and recent research in the clinical and animal experiments on brain injury.
