Polymorphic analysis of 5 Y-SNP loci in Han population of Jinan.
- Author:
Shu-Yi HAN
1
;
Hong-Mei GAO
;
Mao-Xiu ZHANG
;
Yan ZHENG
;
Yan-Fei JIA
;
Bu-Tong DING
;
Yun-Shan WANG
Author Information
1. Jinan Central Hospital Affiliated to Shandong University, Jinan 250013, China. hanshuyi2007@126.com
- Publication Type:Research Support, Non-U.S. Gov't
- MeSH:
Alleles;
Asian People/genetics*;
China/ethnology*;
Chromosomes, Human, Y/genetics*;
Forensic Genetics/methods*;
Gene Frequency;
Genetic Markers;
Haplotypes;
Humans;
Male;
Polymerase Chain Reaction/methods*;
Polymorphism, Single Nucleotide/genetics*
- From:
Journal of Forensic Medicine
2011;27(3):205-210
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate polymorphism distribution of the 5 Y-SNP loci in Jinan Han population, and evaluate their potential in forensic application.
METHODS:Genotyping of 5 Y-SNP loci (M89, M9, M122, M134, M95) were executed in the sample of 103 unrelated Chinese male individuals in Jinan Han population by using fragment length discrepant allele specific PCR (FLDAS-PCR).
RESULTS:In 5 Y-SNP loci, genetic polymorphism were identified in Jinan Han population, and the ranges of gene diversity(GD) were 0.093 3-0.491 2. Twenty different haplotypes were observed and the haplotypes diversity (HD) was 0.867 9. Six different haplogroups were detected according to international association of Y chromosome nomenclature.
CONCLUSION:Five Y-SNP loci and their haplogroups in Jinan Han population are highly polymorphic, which can provide more information for the genetic structure analysis and forensic genetics research in the region.
