Expression of c-jun protein after experimental rat brain concussion.
- Author:
Feng WANG
1
;
Yong-hong LI
Author Information
1. Department of Forensic Medicine, Wannan Medical College, Wuhu 241001, China. wangmaster76@163.com
- Publication Type:Journal Article
- MeSH:
Animals;
Brain/pathology*;
Brain Concussion/pathology*;
Brain Stem/metabolism*;
Cerebral Cortex/metabolism*;
Disease Models, Animal;
Female;
Forensic Pathology;
Immunohistochemistry;
Male;
Neurons/metabolism*;
Proto-Oncogene Proteins c-jun/metabolism*;
Random Allocation;
Rats;
Rats, Sprague-Dawley;
Time Factors
- From:
Journal of Forensic Medicine
2010;26(1):15-17
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe e-jun protein expression after rat brain concussion and explore the forensic pathologic markers following brain concussion.
METHODS:Fifty-five rats were randomly divided into brain concussion group and control group. The expression of c-jun protein was observed by immunohistochemistry.
RESULTS:There were weak positive expression of c-jun protein in control group. In brain concussion group, however, some neutrons showed positive expression of c-jun protein at 15 min after brain concussion, and reach to the peak at 3 h after brain concussion.
CONCLUSION:The research results suggest that detection of c-jun protein could be a marker to determine brain concussion and estimate injury time after brain concussion.
