A new method for calculating paternity index.
- Author:
De-Jian LÜ
1
;
Hui-Ling LU
Author Information
1. Department of Forensic Biology, Zhongshan Medical College of Sun Yat-sen University, Guangzhou 510089, China. lvdejian@mail.sysu.edu.cn
- Publication Type:Journal Article
- MeSH:
Algorithms;
Alleles;
Child;
Female;
Forensic Genetics;
Gene Frequency;
Genotype;
Humans;
Likelihood Functions;
Male;
Parent-Child Relations;
Paternity
- From:
Journal of Forensic Medicine
2009;25(4):271-273
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To introduce a new method for calculating the paternity index (PI).
METHODS:Assuming that each allele from parents has undergone a transition before it segregates and transmits to child. The transition probability is 1 when parent allele is the same as child's, the transition probability is 0 when parent allele is different from the child's. Every allele has a transmission probability with 0.5. Base on these theories, it is easy to gain the probability that child inherits an allele from the alleged father or mother. Thus, the X value (numerator) and Y value (denominator) of PI formula can be calculated, as unknown man provide an allele for child with the allele frequency.
RESULTS:A general formula that calculated the PI for trios, duos and missing child cases was deduced.
CONCLUSION:The new method is practical in all kinds of forensic paternity case.
