The evaluation of Identifiler system in paternity testing.
- Author:
Ting-Zhi QUE
1
;
Pin-Hua YAN
;
Yuan LIN
;
Yan LIU
;
Li LI
Author Information
1. Shanghai Key Laboratory of Forensic Medicine, Institute of Forensic Science, Ministry of Justice, Shanghai 200063, PR China. quetz@ssfjd.cn
- Publication Type:Journal Article
- MeSH:
Alleles;
China;
DNA Fingerprinting/methods*;
Forensic Genetics/methods*;
Genetic Testing/methods*;
Genetics, Population;
Humans;
Microsatellite Repeats;
Mutation;
Paternity;
Polymerase Chain Reaction/methods*;
Probability;
Tandem Repeat Sequences/genetics*
- From:
Journal of Forensic Medicine
2009;25(3):184-186
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the power of Identifiler System for paternity testing.
METHODS:A total of 3 277 paternity testing cases were studied using Identifiler System. The exclusion power and mutation rates of the Identifiler System were analysed in the paternity testing.
RESULTS:The cumulated power of exclusion was 0.999 998 827, and the cumulated discriminating power was 0.999 999 999 999 999 98, respectively. Of the 3 277 cases, paternity was confirmed in 2 863, but excluded in 347. Among this paternity testing, mutations involving a single STR locus were observed in 65 cases, while mutations involving 2 STR loci were observed in 2 cases.
CONCLUSION:The Identifiler System is powerful and reliable for paternity testing.
