Determination of Cr, Cd, As, Tl and Pb in blood by inductively coupled plasma mass spectrometry.
- Author:
Dong MA
1
;
Min SHEN
;
Xian-yi ZHUO
;
Hui YAN
;
Ping XIANG
;
Wei LIU
Author Information
1. Department of Forensic Medicine, Shanghai Medical College, Fudan University, Shanghai 200032, China. madong@ssfjd.cn
- Publication Type:Research Support, Non-U.S. Gov't
- MeSH:
Arsenic/blood*;
Cadmium/blood*;
Chromium/blood*;
Forensic Toxicology;
Humans;
Lead/blood*;
Mass Spectrometry/methods*;
Metals, Heavy/blood*;
Titanium/blood*
- From:
Journal of Forensic Medicine
2009;25(1):37-39
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish an inductively coupled plasma mass spectrometry (ICP-MS) method for determination of Cr, Cd, As, Tl and Pb in blood.
METHODS:The samples were digested by microwave digestion instrument. ICP-MS was applied to determine Cr, Cd, As, Tl and Pb in blood by using 115In as an internal standard.
RESULTS:The limits of detection were in the range of 0.00001-0.00249 microg/L. The accuracy of the method ranged from 90.1% to 110.7% and the precision ranged from 4.0% to 7.9%.
CONCLUSION:The method is accurate and rapid with superior sensitivity and linear range. It could be used in the poisoning cases caused by Cr, Cd, As, Tl and Pb.
