Recent advances of NF-kappaB in nervous system injury.
- Author:
Yun-Ge ZHANG
1
;
Lu-Yang TAO
Author Information
1. Department of Forensic Medicine, Medical College, Soochow University, Suzhou 215123, China. zhangyunge_2006@163.com
- Publication Type:Review
- MeSH:
Alzheimer Disease/metabolism*;
Brain Injuries/metabolism*;
Brain Ischemia/metabolism*;
Forensic Medicine;
Humans;
NF-kappa B/metabolism*;
Reperfusion Injury/metabolism*;
Time Factors
- From:
Journal of Forensic Medicine
2008;24(6):453-456
- CountryChina
- Language:Chinese
-
Abstract:
Diagnosis of nervous system injury is one of the most difficult issues in medical-legal practice. Nowadays, the activation of NF-kappaB has been studied by many researchers in order to find objective evidence and indicators to calculate the injury time and to diagnose the severity of brain injury for forensic practice. It was reviewed that the advances and problems of NF-kappaB and its correlation with nervous system injury and diseases, such as cerebral ischemia, traumatic brain injury, Alzheimer's disease and amyotrophic lateral sclerosis.