Polymorphism of TPH gene T3792A locus in Han ethnic group of north China.
- Author:
Bing WANG
1
;
Bao-Jie WANG
;
Mei DING
;
Hao PANG
;
Zhen ZHANG
;
Hong-Yu GUAN
;
Hong-Tao LU
Author Information
1. School of Forensic Medicine, China Medical University, Shenyang 110001, China. wangbing928@hotmail.com
- Publication Type:Research Support, Non-U.S. Gov't
- MeSH:
Asian People/genetics*;
China/ethnology*;
Forensic Genetics;
Gene Frequency;
Humans;
Paternity;
Polymorphism, Genetic;
Tryptophan Hydroxylase/genetics*
- From:
Journal of Forensic Medicine
2008;24(6):437-438
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the polymorphism of the TPH gene T3792A locus in Han ethnic group of north China and its application value in forensic science.
METHODS:The polymorphism of T3792A locus of the TPH gene was analyzed by the ASPCR of blood samples from 173 unrelated individuals of north Chinese Han population.
RESULTS:The distribution of the T3792A locus polymorphism of the TPH gene in Han ethnic group of north China followed the Hardy-Weinberg law, with the allele A and T gene frequency of 0.486 and 0.514, respectively.
CONCLUSION:The TPH gene T3792A locus shows a very good genetic polymorphism, and may be applied to individual identification and paternity testing.
