Detection of MMP-11 from menstrual blood using immunohistochemistry.
- Author:
Ya-Nan YAO
1
;
Hui-Ling LU
;
Sen CHEN
;
Jing ZHENG
;
Ya-Qing ZHANG
Author Information
1. Department of Forensic Biology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
- Publication Type:Research Support, Non-U.S. Gov't
- MeSH:
Adult;
Endometrium/pathology*;
Female;
Forensic Medicine/methods*;
Humans;
Immunohistochemistry;
Matrix Metalloproteinase 11/analysis*;
Menstrual Cycle/blood*
- From:
Journal of Forensic Medicine
2008;24(1):32-33
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To prove the feasibility of detecting menstrual blood as well as its cellular localization with rabbit-anti-human matrix metalloproteinase-11 (MMP-11) polyclonal antibody.
METHODS:MMP-11 in menstrual blood, peripheral blood, vaginal liquid, aged menstrual bloodstain, and endometrium sections were assayed with SAP immunohistochemistry.
RESULTS:MMP-11 was found only in menstrual samples within stroma and epithelium cells.
CONCLUSION:MMP-11 polyclonal antibody may be applied in the distinction between menstrual blood and venous blood.
