Validation the haplotype polymorphisms of the DXS7424-DXS101 on X-chromosome.
- Author:
Bing YU
1
;
Ya TUO
;
Hong-sheng GUI
;
Sheng-bin LI
Author Information
1. Key Laboratory of Forensic Sciences, National Ministry of Health, Xi'an Jiaotong University, Xi'an, 710061 China. yubing@mail.xjtu.edu.cn
- Publication Type:Validation Study
- MeSH:
Alleles;
China/ethnology*;
Chromosomes, Human, X/genetics*;
Gene Frequency;
Genetic Linkage/genetics*;
Genetics, Population;
Haplotypes;
Humans;
Male;
Polymerase Chain Reaction;
Polymorphism, Genetic;
Tandem Repeat Sequences
- From:
Journal of Forensic Medicine
2007;23(5):342-344
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To validate the genetic characteristics and distribution of DXS7424-DXS101 on X chromosome in Han population.
METHODS:DXS7424 and DXS101 loci were genotyped by PCR, PAGE and silvers stain methods. Their genetic parameters were analyzed by Arlequin software.
RESULTS:There were 37 haplotypes detected in 151 Han unrelated males. The frequencies ranged from 0.0066 to 0.1391, with a GD value of 0.9453 and a DP value of 0.9389. Haplotypes 16-23 were the most common haplotypes in Han population.
CONCLUSION:Analysis of combined DXS7424 and DXS101 haplotypes appears to be a powerful means in population genetics and forensic practice for determination of identity and paternity.
