A study in extraction method of buprenorphine in urine.
- Author:
Dong-xian LIU
1
;
Jiang-nan HE
Author Information
1. Department of Criminal technology, Hunan Public Security College, Changsha 410138, China. liudongxian@yahoo.com.cn
- Publication Type:Research Support, Non-U.S. Gov't
- MeSH:
Buprenorphine/urine*;
Chlorpropham/chemistry*;
Chromatography, Gas/methods*;
Chromatography, Liquid/methods*;
Humans;
Hydrogen-Ion Concentration;
Reproducibility of Results;
Solid Phase Extraction/methods*;
Solvents/chemistry*
- From:
Journal of Forensic Medicine
2007;23(4):292-294
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:The extraction method for separating buprenorphine from urine was described.
METHODS:Buprenorphine was extracted with chloroform at pH7 or with SPE (extracted by organic support 401 at pH10.8, then eluted with chloroform), finally determined by GC-NPD.
RESULTS:The extracted yields of the analyte in specimens were 86.6% by solution-phase extraction and 83.0% by solid-phase extraction (SPE) respectively.
CONCLUSION:These two methods are simple and accurate for separating buprenorphine from urine.
