Relationship between P300 and intelligence quotient in severe head injury patients.
- Author:
Yu-Qing LIU
1
;
Ling-Li ZHANG
;
Xiao-Hong ZHAO
;
Zi-Long LIU
;
Zeng-Hui MEI
Author Information
1. Department of Forensic Medicine, Tongii Medical College of Huazhong University of Science and Technology, Wuhan 430030, China.
- Publication Type:Journal Article
- MeSH:
Adolescent;
Adult;
Aged;
Cognition;
Craniocerebral Trauma/psychology*;
Event-Related Potentials, P300;
Female;
Humans;
Intelligence;
Male;
Middle Aged;
Reaction Time;
Trauma Severity Indices;
Wechsler Scales;
Young Adult
- From:
Journal of Forensic Medicine
2007;23(2):108-113
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the change of brain cognition function in severe head injury and the correlation between P300 in event-related potential (ERP) and intelligence quotient (IQ).
METHODS:Auditory P300 was measured and intelligence quotient was tested by Wechsler Adult Intelligence Scale Revised in China (WAIS-RC) in 40 severe head injury patients. Auditory P300 was measured in 40 normal healthy people as control group.
RESULTS:The latencies of P300 in severe head injury patients group were longer than in control group. There was a significant difference between the two groups (P< 0.01). There were significant negative correlations between P300 latency and VIQ and FIQ respectively (r=-0.335,-0.344, P<0.05).
CONCLUSION:ERP might be taken as an objective index for measuring the change of the brain cognition function in patients with severe head injury.
