Expression of c-myc protein on rats' brains after brain concussion.
- Author:
Wei-Hua FANG
1
;
Dong-Liang WANG
;
Feng WANG
Author Information
1. Department of forensic medicine, Wannan medical college, Wuhu 241001, China. weihua_3110@yahoo.com.cn
- Publication Type:Journal Article
- MeSH:
Animals;
Brain/pathology*;
Brain Concussion/pathology*;
Brain Stem/pathology*;
Cerebral Cortex/pathology*;
Disease Models, Animal;
Female;
Immunohistochemistry;
Male;
Neurons/pathology*;
Proto-Oncogene Proteins c-myc/metabolism*;
Random Allocation;
Rats;
Rats, Sprague-Dawley;
Time Factors
- From:
Journal of Forensic Medicine
2006;22(5):333-334
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the changes of expression of c-myc protein on rats' brains after brain concussion.
METHODS:sixty rats were randomly divided into brain concussion groups and control group. The expression of c-myc protein was microscopically observed by immunohistochemical method.
RESULTS:No expression of c-myc protein in control group were observed. However, positive expression of c-myc protein in some neurons was seen at 20 min after brain concussion, and reach to the peak at 8h after brain concussion and then decreased gradually.
CONCLUSION:These findings suggest that the detection of c-myc protein could be an index of diagnosis of brain concussion.
