Improved method of acute myocardial ischemic rat model.
- Author:
Bin LUO
1
;
Lei XIANG
;
Dong-Hua JIANG
;
Xiao-Ping KONG
;
Neng-Pei ZHANG
;
Yun HE
;
Bin ZHANG
;
Yu YANG
;
Ling-Xi CHENG
Author Information
1. Department of Forensic Medicine, The School of Preclinical Medicine, Sun Yat-sen University, Guangzhou 510080, China. luobin@mail.sysu.edu.cn
- Publication Type:Research Support, Non-U.S. Gov't
- MeSH:
Acute Disease;
Anesthesia, General/methods*;
Animals;
Coronary Vessels/surgery*;
Disease Models, Animal;
Intubation, Intratracheal/methods*;
Ketamine/chemistry*;
Male;
Myocardial Ischemia/pathology*;
Rats;
Rats, Sprague-Dawley
- From:
Journal of Forensic Medicine
2006;22(5):321-323
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To improve the successful rate of operation and the livability in establishing acute myocardial ischemic rat model.
METHODS:The successful rate of animal experiment is compared between traditional method and improved method.
RESULTS:The successful rate of improved method was 90%, which was much higher than 30% in successful rate of traditional method.
CONCLUSION:The improved method may reduce the difficulty of operation remarkably and cut down the experiment expenditure, which is superior to traditional method.
